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Faculty Page for Sungsool Wi
Assistant Professor, Analytical Chemistry
E-mail: sungsool@vt.edu
Office: 3107 Hahn Hall
Phone: 540-231-3329
Fax: 540-231-3255
Education, Honors and Awards
B. S. 1986 Dongguk University, Seoul, Korea
M. S. 1988 Korea Advanced Institute of Science & Technology, Seoul, Korea
Ph. D. 2001 University of Illinois, Chicago
Postdoctoral Fellow 2001-2003 University of California, Berkeley
Postdoctoral Associate 2003-2004 Iowa State University
Research Interests
Solid-state nuclear magnetic resonance spectroscopy is a powerful tool to determine atomic-resolution structure and dynamics in solid systems. Dr. Wi's research focuses on applications of solid-state NMR to problems in membrane-bound biological macromolecules, neurotoxic protein aggregates and modern materials. The present research activities include:
- Structure and dynamics of membrane-bound antimicrobial peptides.
Membrane associated structure of epsin NH2-terminal homology (ENTH) domain.
Structure and supramolecular organization of pathological peptide aggregates.
Selected Publications
- "Long Range 1H-19F Distance Measurement in Peptides by Solid-State NMR," S. Wi, N. Sinha and M. Hong, J. Am. Chem. Soc. 126, 12754-12755 (2004).
- "Solid-State NMR Investigation of the Selective Perturbation of Lipid Bilayers by the Cyclic Antimicrobial Peptide RTD-1," J. J. Buffy, M. J. McCormick, S. Wi, A. Waring, R. I. Lehrer, and M. Hong, Biochemistry 43, 9800-9812 (2004).
- "Rotary Resonance Recouplings of Half-Integer Quadrupolar Nuclei in Solid-State
Nuclear Magnetic Resonance Spectroscopy," S. Wi, J. W. Logan, J. D. Walls,
D. Sakellariou and A. Pines, J. Chem. Phys. 117, 7024-7033 (2002).
- "Reintroducing Anisotropic Interactions in Magic-Angle-Spinning NMR of Half-Integer Quadrupolar Nuclei: 3D MQMAS methods," S. Wi, H. Heise, and A. Pines, J. Am. Chem. Soc. 124, 10652-10653 (2002).
- "Heteronuclear Recoupling in Solid State Magic-Angle-Spinning NMR via Overtone Irradiation," S. Wi and L. Frydman, J. Am. Chem. Soc. 23, 10354-10361 (2001).
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