Richard D. Gandour
Professor
Organic Chemistry
E-mail: gandour@vt.edu
Office: 302 Davidson Hall
Phone: 540-231-3731
Lab Phone: 540-231-7049
Fax: 540-231-3255
Group Web Pages: http://www.files.chem.vt.edu/chem-dept/gandour/gandour_home.html
Research Video Clip: http://www.files.chem.vt.edu/faculty/videos/Gandour.wmv
B.S. Wheeling Jesuit College, 1967
Ph.D. Rice University, 1972
Postdoctoral Fellow, University of Kansas, 1971-75
Visiting Research Scientist, Indiana University, 1989-90
Visiting Professor, UCLA, 1990
Fellow, AAAS
Our most recent work focuses on (1) design and synthesis of affordable anti-infectives and (2) modification of metal oxide surfaces in designing bionano-constructs and responsive thin films.
- Williams, A. A.; Day, B. S.; Kite, B. L.; McPherson, M. K.; Slebodnick, C.; Morris, J. R.; Gandour, R. D. Homologous, Long-chain Alkyl Dendrons Form Homologous Thin Films on Silver Oxide Surfaces. Chem. Commun. 2005, 5053-5055. doi:10.1039/b506710c.
- Karlovská, J.; Williams, A. A.; Macri, R. V.; Gandour, R. D.; Funari, S. S., Uhríková, D.; Balgavy, P. Synchrotron SAX and WAX diffraction study of a hydrated very long-chain, dendritic amphiphile+DPPC mixture. Coll. Surf., B. 2007, 54, 160-164. doi:10.1016/j.colsurfb.2006.10.009.
- Williams, A. A.; Sugandhi, E. W.; Macri, R. V.; Falkinham, J. O., III; Gandour, R. D. Antimicrobial Activity of Long-Chain, Water-Soluble, Dendritic Tricarboxylato Amphiphiles. J. Antimicrob. Chemother. 2007, 51, 451-458. doi:10.1093/jac/dkl503.
- Sugandhi, E. W.; Macri, R. V.; Williams, A. A.; Kite, B. L.; Slebodnick, C.; Falkinham, J., III; Esker, A. R.; Gandour, R. D. Synthesis, Critical Micelle Concentrations, and Antimycobacterial Properties of Homologous, Dendritic Amphiphiles. Probing Intrinsic Activity and the "Cutoff" Effect. J. Med. Chem. 2007, 50, 1645-1650. doi:10.1021/jm061240d.
- Sugandhi, E. W.; Falkinham, J. O., III; Gandour, R. D. Synthesis and Antimicrobial Activity of Symmetrical Two-tailed Dendritic Tricarboxylato Amphiphiles. Bioorg. Med. Chem. 2007, 15, 3842–3853. doi:10.1016/j.bmc.2007.03.017.
- Sugandhi, E. W.; Slebodnick, C.; Falkinham, J., III; Gandour, R. D. Synthesis and antimicrobial evaluation of water-soluble, dendritic derivatives of epimeric 5-α-cholestan-3-amines and 5-α-cholestan-3-yl aminoethanoates. Steroids 2007, 72, 615–626. doi:10.1016/j.steroids.2007.04.001
- Macri, R. V.; Karlovská, J.; Doncel, G. F.; Du, X.; Maisuria, B. B.; Sugandhi, E. W.; Williams, A. A.; Falkinham, J. O., III; Esker, A. R.; Gandour, R. D. Comparing Anti-HIV, Antibacterial, Antifungal, Micellar, and Cytotoxic Properties of Tricarboxylato Dendritic Amphiphiles. Bioorg. Med. Chem. 2009, 17, 3162–3168. dx.doi.org/10.1016/j.bmc.2009.02.055.
